More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer

  title={More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer},
  author={Sebastian P Haen and Philippe L. Pereira and Helmut Rainer Salih and Hans-Georg Rammensee and C{\'e}cile Gouttefangeas},
  booktitle={Clinical & developmental immunology},
Over the past decades, thermoablative techniques for the therapy of localized tumors have gained importance in the treatment of patients not eligible for surgical resection. Anecdotal reports have described spontaneous distant tumor regression after thermal ablation, indicating a possible involvement of the immune system, hence an induction of antitumor immunity after thermoinduced therapy. In recent years, a growing body of evidence for modulation of both adaptive and innate immunity, as well… CONTINUE READING
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