Morbidity associated with MDMA (ecstasy) abuse: A survey of emergency department admissions

@article{Halpern2011MorbidityAW,
  title={Morbidity associated with MDMA (ecstasy) abuse: A survey of emergency department admissions},
  author={Pinchas Halpern and Jenny Moskovich and Beni Avrahami and Yedidia Bentur and Dror Soffer and Kobi Peleg},
  journal={Human \& Experimental Toxicology},
  year={2011},
  volume={30},
  pages={259 - 266}
}
Methods: We conducted a prospective, representative-sample nationwide study on morbidity related to 3,4, methylenedioxymethamphetamine (MDMA; ‘ecstasy’) as determined from admissions to 5 geographically representative emergency departments (EDs) and from data from the poison information center (PIC). MDMArelated ED admissions were analyzed over a 7-month period and the records of all PIC calls were reviewed. Results: There were 52 (age 15—44 years, 32 males) ecstasy-related ED admissions during… Expand
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References

SHOWING 1-10 OF 37 REFERENCES
"Saturday night fever": ecstasy related problems in a London accident and emergency department.
TLDR
For young adults presenting late at night at weekends and exhibiting symptoms of sympathetic overactivity, disturbed behaviour, and increased temperature ("Saturday night fever") the use of stimulant dance drugs especially MDMA should be suspected. Expand
Ecstasy (MDMA) deaths in New York City: a case series and review of the literature.
TLDR
All deaths investigated by the OCME that tested positive for MDMA between January 1997 and June 2000 were reviewed and evidence of recent opiate and/or cocaine use was found in 7 of the acute intoxication deaths and in none of the traumatic or combination natural/intoxication deaths. Expand
Death rates from ecstasy (MDMA, MDA) and polydrug use in England and Wales 1996–2002
TLDR
This is the largest sample of ecstasy related deaths so far; possible explanations are given for the observed steady increase in ecstasy‐related deaths and a tentative ‘rationale’ for this polypharmacy combination is then proposed. Expand
[Analysis of patients attended in an emergency department due to ecstasy consumption].
TLDR
Ecstasy consumption generates common attendance at the Emergency Department and can be potentially fatal. Expand
The Epidemiology of Ecstasy Use and Harms in Australia
TLDR
Messages and interventions to reduce the risks associated with polydrug use and patterns of extended periods of use are clearly warranted and should be delivered outside of traditional health care settings. Expand
Methamphetamine abuse and emergency department utilization.
TLDR
There was a significant association between trauma and MAP use in this patient population and the data suggest MAP users utilize prehospital and hospital resources at levels higher than the average ED population. Expand
Multiple severe complications from recreational ingestion of MDMA ('Ecstasy')
TLDR
A young woman who suffered serious but reversible toxic reactions from a recreational dose of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") and whose blood levels of MDMA were much higher than in any of the fatalities reported by Dowling et al. Expand
Ecstasy and Drug Consumption Patterns: A Canadian Rave Population Study
TLDR
It is found that drug consumption levels were substantial in this “rave” population, particularly with respect to recent use of MDMA, amphetamine, cannabis, and alcohol. Expand
‘Ecstasy’ intoxication: life-threatening manifestations and resuscitative measures in the intensive care setting
TLDR
The increase in life-threatening episodes of 3,4-methylenedioxymethamphetamine intoxication that mandate admission, treatment and close surveillance in an intensive care milieu make it incumbent to establish appropriate management protocols for minimizing immediate mortality and late morbidity. Expand
Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")
The risk of adverse reactions to 3,4-methylenedioxymethamphetamine (MDMA), more commonly known as "ecstasy", is now widely known in both the USA and UK, but the patterns of illness remain varied. WeExpand
...
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