Hospitalizations in the department of pediatrics of the Bangui Hospital (Central Africa) during the year 1990 were evaluated in terms of mortality and morbidity. During the study year, 8,052 children were admitted. Overall in-hospital mortality rate was 11.6%. Most deaths occurred shortly after admission (60% within 24 hours), in patients less than one year of age. Analysis of morbid conditions highlighted the growing severity of malaria and anemia in the youngest patients. Since no other facilities for inpatient treatment of children exist in the area, the data presented here can be considered as reflecting local medical problems and, therefore, can be used to guide public health decisions.