Morbidity and mortality after non‐curative gastrectomy for gastric cancer in elderly patients

  title={Morbidity and mortality after non‐curative gastrectomy for gastric cancer in elderly patients},
  author={Jung Ho Shim and Kyung Jai Ko and Han Mo Yoo and Seong Il Oh and Dong Jin Jeon and Hae Myung Jeon and Cho Hyun Park and Kyo Young Song},
  journal={Journal of Surgical Oncology},
This study examined the surgical outcome of non‐curative resection in elderly patients with gastric cancer. 
The Role of Non-Curative Surgery in Incurable, Asymptomatic Advanced Gastric Cancer
There is a role for non-curative surgery plus first-line chemotherapy for incurable, asymptomatic AGC, in terms of survival and Randomized controlled trials are warranted to fill a gap in knowledge about the value of metastectomy and patient selection strategies.
The Benefits of Resection for Gastric Carcinoma Patients with Non-curative Factors
The current results highlight the improved survival rates of gastric carcinoma patients with non-curative factors who underwent surgery compared with those who did not.
Laparoscopic versus open gastrectomy for elderly local advanced gastric cancer patients: study protocol of a phase II randomized controlled trial
If the rational introduction of minimally invasive surgery technique in traditional gastrectomy can help improve the surgical safety for elderly patients, reduce patient financial burden, shorten hospital stay, and improve hospital beds turnover rate, this research data will provide high quality clinical evidence and data support for the conduction of multicenter phase III clinical trials.
Open and minimally invasive gastrectomy in Eastern and Western patient populations: A review of the literature and reasons for differences in outcomes.
The literature comparing open and minimally invasive gastrectomy in the East and West is reviewed, and the possible reasons for differences in outcomes are described.
Peri-operative Outcomes and Survival Following Palliative Gastrectomy for Gastric Cancer: a Systematic Review and Meta-analysis
Palliative gastrectomy is associated with a small improvement in survival at 1 year when compared to non-resectional surgery and chemotherapy, however, at 2 and 3 years following treatment, survival benefits are less clear.
How could we identify the 'old' patient in gastric cancer surgery? A single centre cohort study.
Comparison of Outcomes for Elderly Gastric Cancer Patients at Least 80 Years of Age Following Gastrectomy in the United States and China
Patients aged 80 years or older selected for gastrectomy for GC at MSKCC and FMUUH had acceptable morbidity and mortality, and DSS was primarily dependent on TNM stage.
Short- and Long-Term Outcomes after Laparoscopic Versus Open Gastrectomy for Elderly Gastric Cancer Patients: A Systematic Review and Meta-analysis.
  • F. Shan, Chao Gao, J. Ji
  • Medicine
    Journal of laparoendoscopic & advanced surgical techniques. Part A
  • 2020
LG was more favorable than OG in the elderly patients <80 years old with gastric cancer in this meta-analysis, and in the subgroup with a cutoff age of 80 years, the anastomotic leakage rate was higher in LG.
MicroRNA-218 is upregulated in gastric cancer after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy and increases chemosensitivity to cisplatin.
The results indicated that targeting miR-218 may provide a strategy for blocking the development of gastric cancer and reverse the multi-drug resistance of Gastric cell lines.


Mortality for gastric cancer in elderly patients
The aim of this study was to clarify the surgical outcome in elderly patients with gastric cancer and to provide guidance on how to select patients suitable for surgery for surgery-like procedures.
Surgical treatment for gastric carcinoma in the elderly
The aim of this study is to evaluate the impact of advanced age (≥80 years) on morbidity, mortality and late outcome after curative surgery for gastric cancer.
Value of palliative resection in gastric cancer
Non‐curatively treated patients from the Dutch Gastric Cancer Trial were studied to define more accurately which patients might benefit from palliative resection.
The survival benefit of resection in patients with advanced stomach cancer: The norwegian multicenter experience
Resection seems justified in patients with advanced stomach cancer since a survival benefit is documented, and survival rates were significantly higher in resected patients than in nonresection or no operation.
Comparison of surgical outcomes of gastric cancer in elderly and middle-aged patients.
Palliative resection in gastric cancer
The study shows that palliative total and partial gastrectomy can produce palliation in advanced gastric cancer.
Surgical Mortality, Survival, and Quality of Life after Resection for Gastric Cancer in the Elderly
Re resection with curative intention can be performed for the elderly with acceptable morbidity and mortality rates, possible long-term survival, and good quality of life, but a limited operation should be considered in the very elderly patients.
A systematic review of surgery for non-curative gastric cancer
A lack of transparent documentation of disease burden and symptoms limits the surgical literature in non-curative gastric cancer, and improved survival is not evident for all patients receiving non-Curative gastrectomy.
Surgery for stomach cancer in a defined Swedish population: current practices and operative results. Swedish Gastric Cancer Study Group.
Surgical treatment of stomach cancer still carries a substantial morbidity and mortality in an unselected series of patients, particularly among elderly patients, and there was no difference in postoperative morbidity or mortality among different types of hospital categories.
Palliation of Metastatic Gastric Cancer: Impact of Preoperative Symptoms and the Type of Operation on Survival and Quality of Life
In patients with incurable gastric cancer the preoperative intensity of symptoms has a significant impact on survival and QoL, which is not influenced by the operation, and preoperative symptoms such as nausea/vomiting and melena were rated significantly higher in patients with major symptoms.