Moral low ground

Abstract

The activity of the transcription factor c-JUN is increased in several human cancers. In their Nature paper, Axel Behrens and colleagues now show that c-JUN is part of a transcriptional complex that is central to the development of colorectal cancer. Loss of the adenomatous polyposis coli gene (APC) predisposes individuals to an increased risk of developing… (More)
DOI: 10.1038/nrc1684

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