Montelukast for treatment of refractory pruritus in patients on hemodialysis.

  title={Montelukast for treatment of refractory pruritus in patients on hemodialysis.},
  author={Ali Reza Nasrollahi and Amirhosein Miladipour and Esmat Ghanei and Parvin Yavari and Farshid Haghverdi},
  journal={Iranian journal of kidney diseases},
  volume={1 2},
INTRODUCTION One of the most common complaints in patients with end-stage renal disease (ESRD) is uremic pruritus. In the recent years, many drugs have been proposed for its treatment which have had paradoxical outcomes. We studied the antipruritus effect of montelukast sodium, a leukotriene receptor antagonist, in patients on hemodialysis. MATERIALS AND METHODS The study was conducted as randomized, single-blind, placebo-controlled crossover study in 5 hemodialysis centers. Sixteen patients… CONTINUE READING