Monte Carlo studies of the thermodynamics and kinetics of reduced protein models : Application to small helical , b , and a / b proteins

@inproceedings{Kolinskia1998MonteCS,
  title={Monte Carlo studies of the thermodynamics and kinetics of reduced protein models : Application to small helical , b , and a / b proteins},
  author={Andrzej Kolinskia and Wojciech Galazka and Jeffrey Skolnickb},
  year={1998}
}
Employing a high coordination lattice model and conformational sampling based on dynamic and entropy sampling Monte Carlo protocols, computer experiments were performed on three small globular proteins, each representing one of the three secondary structure classes. The goal was to explore the thermodynamic character of the conformational transition and possible mechanisms of topology assembly. Depending on the stability of isolated elements of secondary structure, topology assembly can proceed… CONTINUE READING