Monte Carlo simulation of the kinetics of protein adsorption.

@article{Zhdanov1998MonteCS,
  title={Monte Carlo simulation of the kinetics of protein adsorption.},
  author={Vladimir P. Zhdanov and Bengt Kasemo},
  journal={Proteins},
  year={1998},
  volume={30 2},
  pages={177-82}
}
Adsorption of proteins occurs via diffusion toward the interface, actual adsorption, and subsequent irreversible conformational changes resulting in denaturation of the native protein structure. The conventional kinetic models describing these steps are based on the assumption that the denaturation transitions obey the first-order law with a single value of the denaturation rate constant kappar. Meanwhile, recent Monte Carlo simulations indicate that, in general, the denaturation process cannot… CONTINUE READING