Monozygotic twins discordant for the Russell-Silver syndrome.

  title={Monozygotic twins discordant for the Russell-Silver syndrome.},
  author={Wendi Bailey and Bradley Popovich and Kenneth Lyons Jones},
  journal={American journal of medical genetics},
  volume={58 2},
Russell-Silver syndrome (RSS) is a pattern of malformation characterized by intrauterine and postnatal growth retardation, limb asymmetry, triangular face, and hypospadias. We report on a patient, from a triplet pregnancy, who was one of identical male twins discordant for RSS. R.B. was a 710-g male born at 33 weeks of gestation, with hypospadias, chordee, and undescended testes. He had a normal 46,XY karyotype and no renal abnormalities. Female triplet A weighed 1,843 g, and male triplet B… CONTINUE READING