Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice.

@article{Holloway2013MonosynapticGA,
  title={Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice.},
  author={Benjamin B. Holloway and Ruth L Stornetta and Genrieta Bochorishvili and Alev Erisir and Kenneth E. Viar and Patrice G Guyenet},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2013},
  volume={33 48},
  pages={
          18792-805
        }
}
The C1 neurons, located in the rostral ventrolateral medulla (VLM), are activated by pain, hypotension, hypoglycemia, hypoxia, and infection, as well as by psychological stress. Prior work has highlighted the ability of these neurons to increase sympathetic tone, hence peripheral catecholamine release, probably via their direct excitatory projections to sympathetic preganglionic neurons. In this study, we use channelrhodopsin-2 (ChR2) optogenetics to test whether the C1 cells are also capable… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

The orexinergic neurons receive synaptic input from C1 cells in rats.

VIEW 5 EXCERPTS
CITES BACKGROUND & METHODS

Central fatigue theory and endurance exercise: Toward an interoceptive model

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Next-Generation Tools to Study Autonomic Regulation In Vivo

VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 76 REFERENCES

A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping.

VIEW 18 EXCERPTS
HIGHLY INFLUENTIAL

Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice.

VIEW 8 EXCERPTS

Optical induction of synaptic plasticity using a light-sensitive channel

VIEW 17 EXCERPTS
HIGHLY INFLUENTIAL