Monospecific monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) and to keratin 10 as markers of epidermal differentiation.

@article{Leigh1993MonospecificMA,
  title={Monospecific monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) and to keratin 10 as markers of epidermal differentiation.},
  author={Irene M. Leigh and Patricia E. Purkis and Paul Whitehead and E. Birgitte Lane},
  journal={The British journal of dermatology},
  year={1993},
  volume={129 2},
  pages={110-9}
}
Monospecific antibodies to individual keratin polypeptides can be used to examine the tissue and cellular coexpression of members of keratin pairs. Monospecific monoclonal and polyclonal antibodies have been raised to keratins 1 and 10 using both crude cytoskeletal extracts and synthetic peptides. The tissue distribution of these keratins has been determined against a panel of freshly frozen normal tissues from humans, rodents and pigs. Epidermal expression has been examined in psoriatic… CONTINUE READING

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