Monosodium urate test: a new analgesic test by crystal-induced monoarthritis in rats.

@article{Otsuki1990MonosodiumUT,
  title={Monosodium urate test: a new analgesic test by crystal-induced monoarthritis in rats.},
  author={Taisuke Otsuki and Yasuyuki Agatsuma and Hidefumi Jokura and Shinobu Sakurada and Kensuke Kisara and Takashi Yoshimoto},
  journal={Journal of neuroscience methods},
  year={1990},
  volume={33 2-3},
  pages={229-31}
}
The analgesic effects of various agents were evaluated in knee joint monoarthritic rats where arthritis was induced by monosodium urate (MSU) crystals injected into the knee joint cavities. The weight supported by each hind limb was measured quantitatively using pressure transducers, which revealed dose-dependent recovery produced by various analgesics… CONTINUE READING