Monosaccharide autoxidation in health and disease.

  title={Monosaccharide autoxidation in health and disease.},
  author={Paul J. Thornalley},
  journal={Environmental Health Perspectives},
  pages={297 - 307}
The reduction of oxygen by the ene-diol tautomer of simple monosaccharides produces hydrogen peroxide and alpha-oxoaldehydes. This process, termed monosaccharide autoxidation, occurs at physiological pH and temperature and may contribute to the development of several pathological processes. Enolization of the monosaccharide to an ene-diol tautomer is a prerequisite for the reaction of the monosaccharides with oxygen. The reaction kinetics suggest a two step process: the enolization of the… CONTINUE READING
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Pro - oxidant effect of dihydroxyacetone and reducing sugars on the autoxidation of methyl linoleate in emulsions

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The autox - idation of a - hydroxyketones

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