Mononuclear phagocytes of the intestine, the skin, and the lung.

@article{Scott2014MononuclearPO,
  title={Mononuclear phagocytes of the intestine, the skin, and the lung.},
  author={Charlotte Scott and Sandrine Henri and Martin Guilliams},
  journal={Immunological reviews},
  year={2014},
  volume={262 1},
  pages={9-24}
}
Tissues that are in direct contact with the outside world face particular immunological challenges. The intestine, the skin, and the lung possess important mononuclear phagocyte populations to deal with these challenges, but the cellular origin of these phagocytes is strikingly different from one subset to another, with some cells derived from embryonic precursors and some from bone marrow-derived circulating monocytes. Here, we review the current knowledge regarding the developmental pathways… CONTINUE READING
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CCR2+CD103 intestinal dendritic cells develop from DC committed progenitors and induce interleukin 17 production by T cells

  • CL Scott
  • Mucosal Immunol DOI: 10.1038/mi.2014.70
  • 2014
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