Mononeuropathy multiplex associated with acute parvovirus B19 infection: characteristics, treatment and outcome

@article{Lenglet2011MononeuropathyMA,
  title={Mononeuropathy multiplex associated with acute parvovirus B19 infection: characteristics, treatment and outcome},
  author={Timoth{\'e}e Lenglet and Julien Haroche and Aur{\'e}lie Schnuriger and Thierry Maisonobe and Karine Viala and Yanne Michel and F Chelbi and David Grabli and Paul Seror and Antoine Garbarg-Chenon and Zahir Amoura and Pierre Bouche},
  journal={Journal of Neurology},
  year={2011},
  volume={258},
  pages={1321-1326}
}
To describe the characteristics of peripheral neuropathy related to acute parvovirus B19 (B19V) infection. We reviewed clinical, electrophysiological and histological data of three patients with peripheral neuropathy and positive B19V detection (IgG, IgM and PCR) compatible with acute infection. The neuropathy fulfilled criteria for mononeuropathy multiplex (MM). It could be preceded by or concurrent with a limited purpuric eruption, but systemic manifestations were absent. The first… 
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The neuropathies of vasculitis.
Vasculitis related to viral and other microbial agents.
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References

SHOWING 1-10 OF 15 REFERENCES
Vasculitic Neuropathies: An Update
TLDR
Long-term immunosuppressive therapy is required in most cases of vasculitic neuropathy, and high-dose prednisone combined with intravenous pulse or oral daily cyclophosphamide is standard initial therapy.
Neurologic manifestations associated with parvovirus B19 infection.
TLDR
Eighty-one cases of neurologic disease, including encephalitis, meningitis, stroke, and peripheral neuropathy, that were associated with parvovirus B19 infection were reviewed and no differences in the prevalence of sequealae were noted.
Treatment of parvovirus B19-associated polyarteritis nodosa with intravenous immune globulin.
TLDR
A patient who had polyarteritis nodosa associated with parvovirus B19 infection that regressed completely with intravenous immune globulin therapy is described.
Primary and secondary vasculitic neuropathy
TLDR
In all instances symptomatic vasculitis requires corticosteroid to control the inflammatory process and prevent further ischemic nerve lesions.
Acute bilateral carpal tunnel syndrome associated with human parvovirus B19 infection.
TLDR
Three cases of acute bilateral carpal tunnel syndrome associated with parvovirus B19 infection are described as evidenced by serological data and, in one case, by detection of parvoterrorism B19 DNA in blood with use of PCR.
Clinical aspects of parvovirus B19 infection
Parvovirus B19 is a significant human pathogen that causes a wide spectrum of clinical complications ranging from mild, self‐limiting erythema infectiosum in immunocompetent children to lethal
Parvovirus B19 clearance from peripheral blood after acute infection.
TLDR
One patient showed a persistent infection associated with chronic arthritis and was positive for B19 DNA for 1 year without clearance of the virus, followed after acute infection to determine how long the virus is present in blood, even at low titer.
Persistent B19 infection in immunocompetent individuals: implications for transfusion safety.
TLDR
Results demonstrate that persistence of low levels of B19 DNA suggested by cross-sectional studies is frequent in multitransfused patients and that the virus may remain detectable several years after infection in nonimmunodeficient individuals.
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