Monolayers of the lipid derivatives of isoniazid at the air/water interface and the formation of self-assembled nanostructures in water.

@article{Jin2008MonolayersOT,
  title={Monolayers of the lipid derivatives of isoniazid at the air/water interface and the formation of self-assembled nanostructures in water.},
  author={Yiguang Jin and Shufeng Chen and Rui Xin and Yisheng Zhou},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2008},
  volume={64 2},
  pages={229-35}
}
Isoniazid (INH, isonicotinic acid hydrazide) is one of the most commonly used anti-tubercular drugs. However, resistance of Mycobacterium tuberculosis strains to anti-mycobacterial agents including INH is an increasing problem worldwide. Development of new anti-mycobacterial agents thus has attracted attention. Five lipid derivatives of INH were prepared in this study. They formed monolayers at the air/water interface, and some nanostructures with different morphologies were obtained through… CONTINUE READING
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