Monolayer–multilayer transitions in a lung surfactant model: IR reflection–absorption spectroscopy and atomic force microscopy

@article{Wang2004MonolayermultilayerTI,
  title={Monolayer–multilayer transitions in a lung surfactant model: IR reflection–absorption spectroscopy and atomic force microscopy},
  author={Lin Wang and Peng Cai and Hans-Joachim Galla and Huixin He and Carol R Flach and Richard Mendelsohn},
  journal={European Biophysics Journal},
  year={2004},
  volume={34},
  pages={243-254}
}
A hydrophobic pulmonary surfactant protein, SP-C, has been implicated in surface-associated activities thought to facilitate the work of breathing. Model surfactant films composed of lipids and SP-C display a reversible transition from a monolayer to surface-associated multilayers upon compression and expansion at the air/water (A/W) interface. The molecular-level mechanics of this process are not yet fully understood. The current work uses atomic force microscopy on Langmuir–Blodgett films to… CONTINUE READING
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