Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury

@inproceedings{Zakrzewicz2015MonocyticTT,
  title={Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury},
  author={Anna Teresa Zakrzewicz and Srebrena Atanasova and Winfried Padberg and Veronika Grau},
  booktitle={Mediators of inflammation},
  year={2015}
}
Acute rejection is a major risk factor for chronic allograft injury (CAI). Blood leukocytes interacting with allograft endothelial cells during acute rejection were suggested to contribute to the still enigmatic pathogenesis of CAI. We hypothesize that tissue transglutaminase (Tgm2), a multifunctional protein and established marker of M2 macrophages, is… CONTINUE READING