Monocytes primed with GTS-21/α7 nAChR (nicotinic acetylcholine receptor) agonist develop anti-inflammatory memory.


Background The neural system can finely tune immune system, especially pro- or anti-inflammatory responses of monocytes/macrophages. To maintain immune homeostasis, monocytes/macrophages are supposed to be primed by α7 nAChR agonist to establish anti-inflammatory memory. Aim To study whether activation of α7 nAChR would elicit anti-inflammatory memory in… (More)
DOI: 10.1093/qjmed/hcx014


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