Monocytes play different roles in stimulating T cells in obese diabetic individuals.

@article{Dai2015MonocytesPD,
  title={Monocytes play different roles in stimulating T cells in obese diabetic individuals.},
  author={Xiaojiang Dai and Junfang Zhan and Todd A Demmy and Fred B. Poordad and Paulette L. Fauceglia and Hong-bin Zhang and Liangping Wu},
  journal={International journal of immunopathology and pharmacology},
  year={2015},
  volume={28 3},
  pages={374-83}
}
Type 2 diabetes (T2D) is a chronic metabolic disorder, which was also found to involve a series of inflammatory disorders, including accumulation of macrophages and T cells in the adipose tissue, increased proinflammatory cytokine production, shifting of macrophage composition toward M1-type, and skewing of peripheral blood T cells toward IL-17 productions. However, these studies were primarily conducted in obese mouse models and/or human subjects with higher BMI, and may not reflect the role… CONTINUE READING
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