Monocyte chemotactic protein-1 and its role in insulin resistance

  title={Monocyte chemotactic protein-1 and its role in insulin resistance},
  author={Henrike Sell and J{\"u}rgen Eckel},
  journal={Current Opinion in Lipidology},
  • H. Sell, J. Eckel
  • Published 1 June 2007
  • Biology, Medicine
  • Current Opinion in Lipidology
Purpose of review In obesity, there is a strong link between increased adipose tissue mass and development of insulin resistance in tissues such as liver and muscle. Under these conditions, adipose tissue synthesizes various pro-inflammatory chemokines such as monocyte chemotactic protein-1. This review provides a summary of recent knowledge on the role of monocyte chemotactic protein-1 in adipose tissue inflammation and insulin resistance. Recent findings Monocyte chemotactic protein-1 is a… 

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  • 2003
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