Monocyte chemoattractant protein-1 gene (MCP-1) polymorphisms are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.

@article{AngelesMartnez2015MonocyteCP,
  title={Monocyte chemoattractant protein-1 gene (MCP-1) polymorphisms are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.},
  author={Javier Angeles-Mart{\'i}nez and Rosalinda Posadas-S{\'a}nchez and Edith {\'A}lvarez-Le{\'o}n and Teresa Villarreal-Molina and Guillermo Celestino Cardoso-Salda{\~n}a and Jos{\'e} Manuel Fragoso and Juan G Ju{\'a}rez-Rojas and Aida X Medina-Urrutia and Carlos Posadas-Romero and Gilberto Vargas-Alarc{\'o}n},
  journal={Immunology letters},
  year={2015},
  volume={167 2},
  pages={125-30}
}
The CC chemokine monocyte chemoattractant protein (MCP)-1/CCL2 is involved in the formation, progression, and destabilization of atheromatous plaques and plays an essential role in postinfarction remodeling. The aim of the present study was to evaluate the role of MCP-1 gene polymorphisms as susceptibility markers for premature coronary artery disease (CAD) and cardiovascular risk factors in the Mexican population. Four MCP-1 gene polymorphisms (rs1024611, rs2857654, rs3760396, and rs1024610… CONTINUE READING
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