Monocyte chemoattractant protein-1 expression correlates with monocyte infiltration in the post-ischemic kidney.

@article{Rice2002MonocyteCP,
  title={Monocyte chemoattractant protein-1 expression correlates with monocyte infiltration in the post-ischemic kidney.},
  author={James C Rice and Jeff S Spence and Deborah L Yetman and Robert L. Safirstein},
  journal={Renal failure},
  year={2002},
  volume={24 6},
  pages={703-23}
}
Chemokines play a prominent role in the acute inflammatory response in several models of kidney disease. We reported that monocyte chemotactic peptide-1 (MCP-1) mRNA is increased by ischemia-reperfusion injury. In this report, we examined the effects of ischemia-reperfusion injury on the kinetics and location of MCP-1 protein expression, the excretion of MCP- 1 protein in the urine and on the infiltration of mononuclear cells in the kidney. Pair-fed Sprague-Dawley rats underwent bilateral renal… CONTINUE READING