Monocyte activation and differentiation augment human endogenous retrovirus expression: implications for inflammatory brain diseases.

@article{Johnston2001MonocyteAA,
  title={Monocyte activation and differentiation augment human endogenous retrovirus expression: implications for inflammatory brain diseases.},
  author={Jillian Johnston and Claudia Silva and Janet Holden and Kenneth G. Warren and Arthur W Clark and Christopher Power},
  journal={Annals of neurology},
  year={2001},
  volume={50 4},
  pages={434-42}
}
Human endogenous retroviruses (HERVs) have been implicated as causative agents in diseases characterized by inflammation and macrophage activation, such as multiple sclerosis. Because monocyte activation and differentiation influence retroviral transcription and replication, we investigated the contribution of these processes to the expression of four HERV… CONTINUE READING