Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes

@inproceedings{Passacquale2011MonocytePlateletII,
  title={Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes},
  author={Gabriella Passacquale and Padman Vamadevan and Luis L{\^e}nin Vicente Pereira and Colleen Hamid and Valerie M. Corrigall and Albert Ferro},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Activated platelets exert a pro-inflammatory action that can be largely ascribed to their ability to interact with leukocytes and modulate their activity. We hypothesized that platelet activation and consequent formation of monocyte-platelet aggregates (MPA) induces a pro-inflammatory phenotype in circulating monocytes. METHODOLOGY/PRINCIPAL FINDINGS CD62P(+) platelets and MPA were measured, and monocytes characterized, by whole blood flow cytometry in healthy subjects, before and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…