Monoclonal gammopathy and neuropathy: myelin-associated glycoprotein reactivity and clinical characteristics.

@article{Hafler1986MonoclonalGA,
  title={Monoclonal gammopathy and neuropathy: myelin-associated glycoprotein reactivity and clinical characteristics.},
  author={David A. Hafler and Desmond Johnson and John P. J. Kelly and Hillel S. Panitch and R J Kyle and Howard L. Weiner},
  journal={Neurology},
  year={1986},
  volume={36 1},
  pages={75-8}
}
Immunoblot analysis was performed on the serum from 29 patients with polyneuropathy and monoclonal gammopathy. Nine patients had IgM spikes, and six of the nine had reactivity against myelin-associated glycoprotein (MAG) associated with a slowly progressive, predominantly sensory neuropathy. In contrast, 23 patients who lacked anti-MAG reactivity had more severe sensory motor neuropathy. Thus, IgM monoclonal gammopathy with reactivity against MAG may define a distinct clinical entity. 

From This Paper

Topics from this paper.
17 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…