Monoclonal antibody pharmacokinetics and pharmacodynamics.

@article{Wang2008MonoclonalAP,
  title={Monoclonal antibody pharmacokinetics and pharmacodynamics.},
  author={Weirong Wang and E. Q. Wang and Joseph P Balthasar},
  journal={Clinical pharmacology and therapeutics},
  year={2008},
  volume={84 5},
  pages={548-58}
}
More than 20 monoclonal antibodies have been approved as therapeutic drugs by the US Food and Drug Administration, and it is quite likely that the number of approved antibodies will double in the next 7-10 years. Antibody drugs show several desirable characteristics, including good solubility and stability, long persistence in the body, high selectivity and specificity, and low risk for bioconversion to toxic metabolites. However, many antibody drugs demonstrate attributes that complicate drug… CONTINUE READING
Highly Influential
This paper has highly influenced 23 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.
282 Citations
50 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 282 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…