Monoclonal antibody analysis of serotype-restricted and unrestricted bluetongue viral antigenic determinants.

Abstract

Twenty-one monoclonal antibodies that react with bluetongue virus (BTV) and have restricted or unrestricted serotype specificities were identified in culture supernatants of hybridomas derived from lymphocytes of mice immunized with BTV serotype 17. Hybridomas were screened and antibody specificities characterized in a solid-phase radioimmunoassay and by… (More)

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@article{Appleton1983MonoclonalAA, title={Monoclonal antibody analysis of serotype-restricted and unrestricted bluetongue viral antigenic determinants.}, author={Judith A. Appleton and Geoffrey J. Letchworth}, journal={Virology}, year={1983}, volume={124 2}, pages={286-99} }