Monoclonal antibodies to human intermediate filament proteins. III. Analysis of tumors.

@article{Gown1985MonoclonalAT,
  title={Monoclonal antibodies to human intermediate filament proteins. III. Analysis of tumors.},
  author={Allen M. Gown and Andreas M. Vogel},
  journal={American journal of clinical pathology},
  year={1985},
  volume={84 4},
  pages={413-24}
}
A panel of monoclonal antibodies to human intermediate filament proteins was tested on an unselected series of 246 neoplasms. The antibody panel includes two different anti-cytokeratin antibodies, an anti-vimentin antibody, and an anti-neurofilament antibody (Gown and Vogel, Am J Pathol 114:309, 1984). The studies were done on Carnoy's or methacarn-fixed, paraffin-embedded tissue. When used as a panel, they can unequivocally distinguish carcinomas, melanomas, and lymphomas. All carcinomas react… CONTINUE READING