Monoclonal antibodies to a 140,000-m.w. protein on Plasmodium knowlesi merozoites inhibit their invasion of rhesus erythrocytes.

@article{Miller1984MonoclonalAT,
  title={Monoclonal antibodies to a 140,000-m.w. protein on Plasmodium knowlesi merozoites inhibit their invasion of rhesus erythrocytes.},
  author={Louis H. Miller and Peter H. David and Douglas Hudson and Tricia J. Hadley and Roberta L Richards and Masamichi Aikawa},
  journal={Journal of immunology},
  year={1984},
  volume={132 1},
  pages={438-42}
}
Merozoites are the invasive stage of the malaria parasite, which are released from infected erythrocytes to invade other erythrocytes. Antibody to surface antigens on merozoites may prevent invasion by agglutinating merozoites as they are released from infected erythrocytes or by blocking receptors before contact of merozoites with the host erythrocyte. Monoclonal antibodies were produced to a 140,000-m.w. protein on the merozoite surface. The protein was synthesized by the mature… CONTINUE READING

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