Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.

Abstract

Two-dimensional gel electrophoresis has allowed the detection of proteins characteristic of inner cell mass and trophectoderm in mouse blastocyst. Certain of the proteins characterizing trophectoderm copurify with intermediate filaments from trophectoderm and a trophoblastoma cell line. A monoclonal antibody prepared against proteins of these intermediate filaments labels a filament network in trophectoderm but not in inner cell mass cells.

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@article{Brlet1980MonoclonalAA, title={Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.}, author={Philippe Br{\^u}let and Charles Babinet and Rolf Kemler and Francis Jacob}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1980}, volume={77 7}, pages={4113-7} }