Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.

@article{Bail1990MonoclonalAA,
  title={Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.},
  author={Vladim{\'i}r Ba{\vz}il and Irena {\vS}tefanov{\'a} and Ivan Hilgert and Hana Kri{\vs}tofov{\'a} and Sharon Vanek and V{\'a}clav Hor̆ejs̆{\'i}},
  journal={Folia biologica},
  year={1990},
  volume={36 1},
  pages={41-50}
}
Six monoclonal antibodies were prepared that recognize a broadly expressed antigen composed of noncovalently associated 95 kDa and 180 kDa subunits. Antibodies MEM-25, MEM-83 and MEM-95 are shown to react with a determinant(s) present on the isolated larger subunit identified as the CD11a glycoprotein, MEM-48 reacts with the isolated smaller subunit which is identical to the CD18 glycoprotein. Antibodies MEM-30 and MEM-94 recognize probably a determinant in the CD11a/CD18 complex (i.e., LFA-1… CONTINUE READING