Monoclonal antibodies against beta-2-glycoprotein I: use as reference material for lupus anticoagulant tests.

The laboratory diagnosis of lupus anticoagulants (LA) remains difficult despite internationally accepted guidelines for its detection. Several interlaboratory surveys have shown poor agreement between laboratories. Further standardization of LA testing will to a large extent depend on better insights on the mechanisms by which LA affect phospholipid… CONTINUE READING