Monoclonal antibodies against ICAM-1 and CD18 attenuate cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits.

@article{Bavbek1998MonoclonalAA,
  title={Monoclonal antibodies against ICAM-1 and CD18 attenuate cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits.},
  author={Murad Bavbek and Richard A. Polin and A. L. Kwan and Adam Stephen Arthur and Neal F. Kassell and Kevin Sang Lee},
  journal={Stroke},
  year={1998},
  volume={29 9},
  pages={1930-5; discussion 1935-6}
}
BACKGROUND AND PURPOSE Inflammatory responses have been implicated in the elaboration of several forms of central nervous system injury, including cerebral vasospasm after subarachnoid hemorrhage (SAH). A critical event participating in such responses is the recruitment of circulating leukocytes into the inflammatory site. Two of the key adhesion molecules responsible for the attachment of leukocytes to endothelial cells are intercellular adhesion molecule-1 (ICAM-1) and the common beta chain… CONTINUE READING
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Activated complement components C 3 a and C 4 a in cerebrospinal fluid and plasma following subarachnoid hemorrhage

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