Monoclonal antibodies against Caprine arthritis-encephalitis virus epitopes in the p28 and p55(gag) viral proteins.

The genome of the Caprine Arthritis-Encephalitis Virus (CAEV) encodes the polycistronic precursor protein p55(gag). Proteolytic cleavage of p55(gag) generates the viral core proteins. Some studies suggest that the CAEV p55(gag) protein contains epitopes or antigenic determinants for these core proteins. This work reinforces this hypothesis and demonstrates… CONTINUE READING