Monoclonal B-cell lymphocytosis in first-degree relatives of patients with sporadic (non-familial) chronic lymphocytic leukaemia.

@article{Matos2009MonoclonalBL,
  title={Monoclonal B-cell lymphocytosis in first-degree relatives of patients with sporadic (non-familial) chronic lymphocytic leukaemia.},
  author={Daniel Mazza Matos and Sebasti{\~a}o Jos{\'e} Ismael and Carlos Alberto Scrideli and F{\'a}bio Morato de Oliveira and Eduardo M Rego and Roberto Passeto Falc{\~a}o},
  journal={British journal of haematology},
  year={2009},
  volume={147 3},
  pages={339-46}
}
Although biological similarities have been described among monoclonal B-cell lymphocytosis (MBL) and chronic lymphocytic leukaemia (CLL), the relationships between these two conditions are not fully understood, and new epidemiological studies in different populations and different countries continue to be reported. Here, we investigated 167 first-degree relatives from 42 families of patients with non-familial (sporadic) CLL, using four-colour flow cytometry. MBL was found in seven of 167… CONTINUE READING

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