Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.

@article{Baldwin2015MonocarbonylAO,
  title={Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis.},
  author={Patrick R Baldwin and Analise Z. Reeves and Kimberly R. Powell and Ruth J Napier and Alyson I. Swimm and Aiming Sun and Kyle E. Giesler and Bettina R Bommarius and Thomas M. Shinnick and James P. Snyder and Dennis C Liotta and Daniel Kalman},
  journal={European journal of medicinal chemistry},
  year={2015},
  volume={92},
  pages={693-9}
}
Tuberculosis (TB) is a major public health concern worldwide with over 2 billion people currently infected. The rise of strains of Mycobacterium tuberculosis (Mtb) that are resistant to some or all first and second line antibiotics, including multidrug-resistant (MDR), extensively drug resistant (XDR) and totally drug resistant (TDR) strains, is of particular concern and new anti-TB drugs are urgently needed. Curcumin, a natural product used in traditional medicine in India, exhibits anti… CONTINUE READING

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