Monoamine oxidase inhibitors from Gentiana lutea.

@article{Haraguchi2004MonoamineOI,
  title={Monoamine oxidase inhibitors from Gentiana lutea.},
  author={Hiroyuki Haraguchi and Yasumasa Tanaka and Amal M. Kabbash and Toshihiro Fujioka and Takashi Ishizu and Akira Yagi},
  journal={Phytochemistry},
  year={2004},
  volume={65 15},
  pages={
          2255-60
        }
}
Three monoamine oxidase (MAO) inhibitors were isolated from Gentiana lutea. Their structures were elucidated to be 3-3''linked-(2'-hydroxy-4-O-isoprenylchalcone)-(2'''-hydroxy-4''-O-isoprenyldihydrochalcone) (1), 2-methoxy-3-(1,1'-dimethylallyl)-6a,10a-dihydrobenzo(1,2-c)chroman-6-one and 5-hydroxyflavanone. These compounds, and the hydrolysis product of 1, displayed competitive inhibitory properties against MAO-B which was more effective than MAO-A. 
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