Monoamine depletion in psychiatric and healthy populations: review

  title={Monoamine depletion in psychiatric and healthy populations: review},
  author={L. Booij and A. J. W. Does and W. Riedel},
  journal={Molecular Psychiatry},
  • L. Booij, A. J. W. Does, W. Riedel
  • Published 2003
  • Psychology, Medicine
  • Molecular Psychiatry
  • A number of techniques temporarily lower the functioning of monoamines: acute tryptophan depletion (ATD), alpha-methyl-para-tyrosine (AMPT) and acute phenylalanine/tyrosine depletion (APTD). This paper reviews the results of monoamine depletion studies in humans for the period 1966 until December 2002. The evidence suggests that all three interventions are specific, in terms of their short-term effects on one or two neurotransmitter systems, rather than on brain protein metabolism in general… CONTINUE READING
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