Monoamine Oxidase Inhibitors: Safety and Efficacy Issues

@article{Brown1988MonoamineOI,
  title={Monoamine Oxidase Inhibitors: Safety and Efficacy Issues},
  author={C. S. Brown and Stephen G. Bryant},
  journal={Annals of Pharmacotherapy},
  year={1988},
  volume={22},
  pages={232 - 235}
}
Controversy has historically centered on the use of monoamine oxidase inhibitors (MAOI) in the treatment of depression because of safety and efficacy issues. Hypertensive crisis following ingestion of foods containing tyramine is the most feared problem associated with MAOI therapy. The authors conclude that only four tyramine-containing foods clearly warrant absolute prohibition, but indicate situations where moderation should apply. Although MAOI remain second-line agents in the treatment of… Expand
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