Mono-2-ethyhexyl phthalate advancing the progression of prostate cancer through activating the hedgehog pathway in LNCaP cells.

@article{Yong2016Mono2ethyhexylPA,
  title={Mono-2-ethyhexyl phthalate advancing the progression of prostate cancer through activating the hedgehog pathway in LNCaP cells.},
  author={Wang Yong and Chen Jiao and Wu Jianhui and Zhao Yan and Pan Qi and Wang Xiu and Sun Zuyue and Zhang Yunhui},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2016},
  volume={32},
  pages={86-91}
}
Hedgehog (Hh) pathway plays a critical role in the progression of prostate cancer (PCa), the most commonly diagnosed non-cutaneous cancer in male adults. Studies showed that di-n-butyl phthalate (DBP) could interference with the Hh pathway. Di-2-ethylhexyl phthalate (DEHP), the congener of DBP, is the major plasticizer used in plastic materials that are… CONTINUE READING