Monkeypox Transmission and Pathogenesis in Prairie Dogs

@inproceedings{Guarner2004MonkeypoxTA,
  title={Monkeypox Transmission and Pathogenesis in Prairie Dogs},
  author={Jeannette Guarner and Bill J. Johnson and Christopher D Paddock and Wenping Shieh and Cynthia S. Goldsmith and Mary G. Reynolds and Inger K. Damon and Russell Lawrence Regnery and Sherif R Zaki},
  booktitle={Emerging infectious diseases},
  year={2004}
}
During May and June 2003, the first cluster of human monkeypox cases in the United States was reported. Most patients with this febrile vesicular rash illness presumably acquired the infection from prairie dogs. Monkeypox virus was demonstrated by using polymerase chain reaction in two prairie dogs in which pathologic studies showed necrotizing bronchopneumonia, conjunctivitis, and tongue ulceration. Immunohistochemical assays for orthopoxviruses demonstrated abundant viral antigens in surface… CONTINUE READING

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