Monitoring the rotary motors of single FoF1-ATP synthase by synchronized multi channel TCSPC

@inproceedings{Zarrabi2007MonitoringTR,
  title={Monitoring the rotary motors of single FoF1-ATP synthase by synchronized multi channel TCSPC},
  author={Nawid Zarrabi and Monika G. D{\"u}ser and Stefan Ernst and Rolf Reuter and Gary D Glick and Stanley D Dunn and J. Wrachtrup and Michael B{\"o}rsch},
  booktitle={SPIE Optics East},
  year={2007}
}
Confocal time resolved single-molecule spectroscopy using pulsed laser excitation and synchronized multi channel time correlated single photon counting (TCSPC) provides detailed information about the conformational changes of a biological motor in real time. We studied the formation of adenosine triphosphate, ATP, from ADP and phosphate by FoF1-ATP synthase. The reaction is performed by a stepwise internal rotation of subunits of the lipid membrane-embedded enzyme. Using Förster-type… 

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