Monitoring the response of circulating epithelial tumor cells to adjuvant chemotherapy in breast cancer allows detection of patients at risk of early relapse.

@article{Pachmann2008MonitoringTR,
  title={Monitoring the response of circulating epithelial tumor cells to adjuvant chemotherapy in breast cancer allows detection of patients at risk of early relapse.},
  author={K. Pachmann and O. Camara and A. Kavallaris and S. Krauspe and Nele Malarski and M. Gajda and T. Kroll and C. J{\"o}rke and U. Hammer and A. Altendorf-hofmann and C. Rabenstein and U. Pachmann and I. Runnebaum and K. H{\"o}ffken},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2008},
  volume={26 8},
  pages={
          1208-15
        }
}
  • K. Pachmann, O. Camara, +11 authors K. Höffken
  • Published 2008
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE To demonstrate that it is possible to monitor the response to adjuvant therapy by repeated analysis of circulating epithelial tumor cells (CETCs) and to detect patients early who are at risk of relapse. PATIENTS AND METHODS In 91 nonmetastatic primary breast cancer patients, CETCs were quantified using laser scanning cytometry of anti-epithelial cell adhesion molecule-stained epithelial cells from whole unseparated blood before and during adjuvant chemotherapy. RESULTS Numbers of… Expand
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Efficacy control of therapy using circulating epithelial tumor cells (CETC) as “Liquid Biopsy”: trastuzumab in HER2/neu-positive breast carcinoma
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Prevalence of circulating tumor cells in early breast cancer patients 2 and 5 years after adjuvant treatment
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