Monitoring the nociception level: a multi-parameter approach

  title={Monitoring the nociception level: a multi-parameter approach},
  author={Nir Ben-Israel and Mark Kliger and Galit Zuckerman and Yeshayahu Katz and Ruth Edry},
  journal={Journal of Clinical Monitoring and Computing},
The aim of the present study was to develop and validate an objective index for nociception level (NoL) of patients under general anesthesia, based on a combination of multiple physiological parameters. Twenty-five patients scheduled for elective surgery were enrolled. For clinical reference of NoL, the combined index of stimulus and analgesia was defined as a composite of the surgical stimulus level and a scaled effect-site concentration of opioid. The physiological parameters heart rate… CONTINUE READING
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