Monitoring the growth and drug susceptibility of individual bacteria using asynchronous magnetic bead rotation sensors.

@article{Kinnunen2011MonitoringTG,
  title={Monitoring the growth and drug susceptibility of individual bacteria using asynchronous magnetic bead rotation sensors.},
  author={Paivo Kinnunen and Irene Sinn and Brandon H. McNaughton and Duane W Newton and Mark A. Burns and Raoul Kopelman},
  journal={Biosensors & bioelectronics},
  year={2011},
  volume={26 5},
  pages={2751-5}
}
Continuous growth of individual bacteria has been previously studied by direct observation using optical imaging. However, optical microscopy studies are inherently diffraction limited and limited in the number of individual cells that can be continuously monitored. Here we report on the use of the asynchronous magnetic bead rotation (AMBR) sensor, which is not diffraction limited. The AMBR sensor allows for the measurement of nanoscale growth dynamics of individual bacterial cells, over… CONTINUE READING
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