Monitoring serum concentrations for once-daily netilmicin dosing regimens.

  title={Monitoring serum concentrations for once-daily netilmicin dosing regimens.},
  author={J{\"u}rg Blaser and C. -H. Wirsing von K{\"o}nig and H. P. Simmen and U Thurnheer},
  journal={The Journal of antimicrobial chemotherapy},
  volume={33 2},
A once-daily dosing regimen for aminoglycosides is less expensive, at least as effective and possibly less toxic than multiple-daily dosing regimens. Once-daily dosing might also allow the frequency of measuring the serum concentrations of these antibiotics to be reduced since two of the major objectives of monitoring, high peak and low trough concentrations, are more likely to be achieved with this regimen. A novel strategy for monitoring serum concentrations which relies on a single sample… CONTINUE READING

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