Monitoring of total antimony and its species by ICP-MS and on-line ion chromatography in biological samples from patients treated for leishmaniasis.

@article{Miekeley2002MonitoringOT,
  title={Monitoring of total antimony and its species by ICP-MS and on-line ion chromatography in biological samples from patients treated for leishmaniasis.},
  author={Norbert F Miekeley and Sergio Roberto Mortari and Armando O. Schubach},
  journal={Analytical and bioanalytical chemistry},
  year={2002},
  volume={372 3},
  pages={495-502}
}
Results from a study are reported in which patients with leishmaniasis were monitored by whole blood, blood plasma, urine, and hair analysis, before, during, and after intramuscular administration of N-methyl meglumine antimoniate. Quadrupole ICP-MS was used for the detection of antimony and on-line ion chromatography for the separation of its species. After typically 30 consecutive daily injections of 5 mg antimony per kg of body weight, Sb concentrations of up to 250 microg L(-1) in whole… CONTINUE READING
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Talanta 55 : 1 – 28 3

  • AK Das, M DelaGuardia, ML Cervera
  • WHO Tech Rep Ser
  • 2001

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