Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication

@inproceedings{Bjrs2017MonitoringOT,
  title={Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication},
  author={Karine \O. Bj⊘r{\aa}s and Mirta M. L. Sousa and Animesh Sharma and Davi de Miranda Fonseca and Caroline K. S⊘gaard and Magnar Bj⊘r{\aa}s and Marit Otterlei},
  booktitle={Nucleic acids research},
  year={2017}
}
Base lesions in DNA can stall the replication machinery or induce mutations if bypassed. Consequently, lesions must be repaired before replication or in a post-replicative process to maintain genomic stability. Base excision repair (BER) is the main pathway for repair of base lesions and is known to be associated with DNA replication, but how BER is… CONTINUE READING