Monitoring of solid-phase organic synthesis on macroscopic supports by high-resolution magic angle spinning NMR.

In this paper we demonstrate the efficiency of high-resolution magic angle spinning NMR to monitor solid-phase organic chemistry on macroscopic systems such as Synphase lanterns. The use of the LED sequence eliminates the peaks due to the use of protonated solvents and was also sufficient to decrease the signals due to the matrix. As a direct result, we… CONTINUE READING